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This approach may provide an attractive alternative to directly target the desired oncogene (or protein of another pathogenic activity), focusing instead on developing tools to target the zDHHCs controlling the proper (or pathological) localization of the protein

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The research literature documents benefits ranging from enhanced working memory and accelerated learning to protection against age-related cognitive decline and recovery from neurological injury, with several compounds holding regulatory approval for cognitive indications in countries where peptide therapeutics receive more progressive treatment

CDDO-Me (RTA 402) is effective as single agent and in combination therapy in the 4T1 in vivo model of breast cancer